isotype control ab (13c4) antibody (Genzyme)
Structured Review

Isotype Control Ab (13c4) Antibody, supplied by Genzyme, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/isotype control ab (13c4) antibody/product/Genzyme
Average 90 stars, based on 1 article reviews
Images
1) Product Images from "Blocking TGF-β Signaling Pathway Preserves Mitochondrial Proteostasis and Reduces Early Activation of PDGFRβ+ Pericytes in Aristolochic Acid Induced Acute Kidney Injury in Wistar Male Rats"
Article Title: Blocking TGF-β Signaling Pathway Preserves Mitochondrial Proteostasis and Reduces Early Activation of PDGFRβ+ Pericytes in Aristolochic Acid Induced Acute Kidney Injury in Wistar Male Rats
Journal: PLoS ONE
doi: 10.1371/journal.pone.0157288
Figure Legend Snippet: ( a ) Tissue lysates from kidney cortex were immunoblotted for TGFRβII, VEGFR2, PDGFRβ and glyceraldehyd 3-phosphate dehydrogenase (GAPDH) expression. Bands intensities of TGFRβII protein in studied groups (n = 3 for controls; n = 5 for AA and AA+control Ab groups; and n = 4 for and AA+anti-TGFβ group) were quantified by densitometry. ( b ) The control group displayed a basal level TGFRβII expression, and AA intoxication negatively regulated this expression. Bands intensities of VEGFR2 protein in studied groups (n = 3 for controls; n = 5 for AA and AA+control Ab groups; and n = 3 for and AA+anti-TGFβ group) were quantified by densitometry. ( c ) AA highly increases VEGFR2 expression and anti-TGF Ab had a protective effect. Bands intensities of PDGFRβ protein in studied groups (n = 3 for controls; n = 5 for AA, AA+control Ab and AA+anti-TGFβ groups) were quantified by densitometry. ( d ) Anti-TGF Ab and 13C4 had a protective effect on AA induced increase in PDGFRβ protein expression. Results are presented as means ± SEM. One way ANOVA, *** P < .001, * P < .05 comparison of each group versus control group; followed by Holm Sidak test, ### P < .001, # P < .05 comparison between all groups.
Techniques Used: Expressing, Control, Comparison